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people with overactive bladder or interstitial cystitis don't respond to
the usual medicines. These people may have to void over 15 or 20 times a
day. Getting a good nights sleep for these people is impossible. It is
almost like having a bladder infection that never goes away. The
usual medicines, oxybutinine, tolteridine, trospium, solifenacin and
darifenacin ( trade names are Ditropan, Detrol, Sanctura, Vessicare,
Enablix and Oxytrol) may help up to about 65 % of sufferers.
When the medicines don't work, people's lives may be dominated by
the need to always know where the closest toilet is. There is
another treatment available called Interstim ™. This works sort
of like a pacemaker for the bladder. There is a web site http://www.medtronic.com/patients/bladder.html
maintained by the Medtronic company that has much better and more complete
information than I can provide.
People who are not helped by
overactive bladder medicines or who are not happy about having to be on
the medicines for the rest of their lives may want to look into the
interstim. It is also frequently the treatment of choice for people with
bladder problems related to spinal or nerve damage or multiple
sclerosis.
The treatment begins with a voiding
diary and cystometrogram to accurately diagnose the problem and to exclude
stress incontinence, infection and other things. If the testing shows
overactive bladder and drug therapy not a good alternative, then the
patient may be a candidate for Interstim.
The principle of Interstim therapy
is that stimulation of the pudendal nerve interferes with the bladder
reflexes. If these reflexes are defective and causing symptoms, the
modifying the reflexes may be curative. This principle is used in
several different therapies including peroneal nerve stimulation, and
Neocontrol. There is a conceptual relationship to acupuncture.
The Interstim treatment consists of
inserting a small wire electrode into the opening in the sacrum
where the bladder nerve passes. The test electrode is inserted
through a needle under local anesthesia, frequently in the office,
sometimes in Same-day surgery. The electrode wire is connected to a
temporary generator and the patient wears it for a few days. If the
bladder symptoms improve, usually by about 50%, then we will go to a
permanent system. The permanent electrode is implanted in the sacrum in
the operating room and a permanent generator, much like a pacemaker, is
put under the skin of the buttock. The generator lasts for anywhere
from 4 to 9 years. Most people are aware of a "fluttery" or
tingling sensation in the area of the bladder from the electrode
stimulation. Complications are not common with the procedure, but it is
possible to get infection around the device or to have bleeding or even
nerve damage. These are rare. Somewhat more common is to have the
effectiveness of the stimulation decrease over time. Sometimes this
can be corrected by moving the electrode to the other side of the
sacrum.
If you are having problems with
overactive bladder and the medicines don't seem to help the Interstim may
help. Check out the Medtronic web site or talk to your doctor. Medtronic
maintains a list of doctors who are Interstim qualified . Most
urogynecologists or urologists are familiar with the therapy.
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